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HRID22450

反应详情

EQUATION

反应方程式

HRID 22450 的结构方程式

REACTANTS

反应物

4
结构：CCOCC
HCID3283

Diethyl Ether

C4H10O

结构：O=S(=O)([O-])O.[K+]
HCID516920

Potassium bisulfate

HKO4S

结构：CON(C)C(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C
HCID11119284

未命名化合物

结构：[Al+3].[H-].[H-].[H-].[H-].[Li+]
HCID21226445

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)C[C@@H](C=O)NC(=O)OC(C)(C)C
HCID104275

1,1-Dimethylethyl N-[(1S)-1-formyl-3-methylbutyl]carbamate

C11H21NO3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

Lithium aluminum hydride (2.5 equiv.) is added to a stirred solution of compound (7). Reduction is complete within 15-20 minutes. The mixture is hydrolyzed with a solution of potassium hydrogen sulfate in water. Ether is added and the aqueous phase is separated and extracted. The organic phases are combined, washed with 1N HCl saturated sodium hydrogen carbonate and saturated sodium chloride, and dried with magnesium sulfate. The solvent is evaporated to leave the desired product

WORKUP

后处理

  1. customthe aqueous phase is separated
  2. extractionextracted
  3. washwashed with 1N HCl saturated sodium hydrogen carbonate and saturated sodium chloride
  4. dry with materialdried with magnesium sulfate
  5. customThe solvent is evaporated