Acetic Acid → HCID 58674773, compound

Participants

Reaction Steps

To the thioimidate solution in MeOH (4 mL, 0.063 mmol) from Example 134, a pre-mixed N-methylethylenediamine (0.039 mL, 0.44 mmol) and HOAc (0.080 mL, 1.4 mmol) were added. The mixture was heated to reflux for 1 h, then was stirred at room temperature overnight. After being concentrated in vacuo, the residue was purified by HPLC to give a white powder (15 mg). MS 474.3 and 476.3 (M+H, Cl pattern).

Provenance & Evidence