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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2245086Generated: November 1, 2026

Isopropylamine → HCID 59212716, compound

https://huagongshe.com/reaction/2245086

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
Reactant1,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 67338—
Reactant3-[8-(2,6-Difluorophenyl)-2-(methylthio)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methylbenzoic acidHCID 57530530—
ProductHCID 59212716HCID 59212716—

Reaction Steps

The title compound was prepared from 3-[8-(2,6-difluorophenyl)-2-(methylthio)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methylbenzoic acid by following the procedures in Example 19 using 2-propanamine for the amide formation and N,N,N′-trimethyl-1,2-ethanediamine for the displacement reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07678801B2
Source datasetuspto-grants-2010_03
ORD IDord-d14ba93e05cd4f7b9ad5b5a9e18568ee
Source noteuspto-grants-2010_03