HRID2245096

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID37524

2,2,6,6-Tetramethylpiperidin-4-amine

C9H20N2

结构：Cc1ccc(N)cc1-c1nc(S(C)(=O)=O)nc2c1ccc(=O)n2-c1c(F)cccc1F

HCID59212680

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(N)cc1-c1nc(NC2CC(C)(C)NC(C)(C)C2)nc2c1ccc(=O)n2-c1c(F)cccc1F

HCID44529219

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as described in Example 1d from 4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one and 2,2,6,6-tetramethyl-4-piperidinamine: LC-MS m/z 519 (M+H)+, 1.8 min (ret time).

WORKUP

后处理

customLC-MS m/z 519 (M+H)+, 1.8 min (ret time)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-db7d6c420e7b49d59d44ebb99772f6a0
来源数据集: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07678801B2
来源说明: uspto-grants-2010_03

反应 SMILES

[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:31])=[C:6]([C:8]2[C:9]3[CH:21]=[CH:20][C:19](=[O:22])[N:18]([C:23]4[C:28]([F:29])=[CH:27][CH:26]=[CH:25][C:24]=4[F:30])[C:10]=3[N:11]=[C:12](S(C)(=O)=O)[N:13]=2)[CH:7]=1.[CH3:32][C:33]1([CH3:42])[CH2:38][CH:37]([NH2:39])[CH2:36][C:35]([CH3:41])([CH3:40])[NH:34]1>>[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:31])=[C:6]([C:8]2[C:9]3[CH:21]=[CH:20][C:19](=[O:22])[N:18]([C:23]4[C:28]([F:29])=[CH:27][CH:26]=[CH:25][C:24]=4[F:30])[C:10]=3[N:11]=[C:12]([NH:39][CH:37]3[CH2:38][C:33]([CH3:42])([CH3:32])[NH:34][C:35]([CH3:41])([CH3:40])[CH2:36]3)[N:13]=2)[CH:7]=1