Nitric Acid → 2-(Carboxymethyl)-5-nitrobenzoic acid

HRID 2245276Notes

Reaction equation

HRID 2245276 reaction equation
[C:1]([CH2:4][C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[C:7]([OH:9])=[O:8])([OH:3])=[O:2].[N+:14]([O-])([OH:16])=[O:15]>>[N+:14]([C:11]1[CH:12]=[CH:13][C:5]([CH2:4][C:1]([OH:3])=[O:2])=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8])([O-:16])=[O:15]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 66643Homophthalic acid

Product 1

HCID 123034522-(Carboxymethyl)-5-nitrobenzoic acid

Procedure

3.0 g of 2-carboxymethyl-benzoic acid were dissolved in 16 ml of fuming nitric acid. 16 ml of ice water was added into the resulting solution after stirred at room temperature for 2 hr, then filtrated to obtain a precipitation, dried in vacuum to obtain 1.99 g of 5-nitro-2-carboxymethyl-benzoic acid.

Workup

  1. filtrationfiltrated
  2. customto obtain
  3. customa precipitation
  4. customdried in vacuum

Sources & evidence

ORD record
ord-38278367671246c3a5adbe8730474070
Source dataset
uspto-grants-2010_03
Patent number
US07683073B2

Reaction notes

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