Methyl 6-Bromohexanoate → HCID 67319949, compound
Reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[C:8]([C:10]3[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=3)[N:7]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)[C:6]=2[CH:23]=1.[CH3:24][O:25][C:26](=[O:33])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]Br>>[CH3:24][O:25][C:26](=[O:33])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][O:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[C:8]([C:10]3[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=3)[N:7]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)[C:6]=2[CH:23]=1Participants
3
Procedure
6-Hydroxy-1-(4-fluorophenyl)-2-(3-pyridinyl)-1H-benzimidazole was reacted with 6-bromohexanoic acid methyl ester according to general operating instructions 3.
Sources & evidence
- ORD record
- ord-40815e9b288d4807ab46ce34d53d1819
- Source dataset
- uspto-grants-2010_03
- Patent number
- US07683081B2
Reaction notes
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