Sodium Hydroxide → 4-[(5-Nitro-1H-indol-1-yl)methyl]benzoic acid

HRID 2245513Notes

Reaction equation

HRID 2245513 reaction equation
[OH-].[Na+].[N+:3]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[N:11]([CH2:15][C:16]1[CH:25]=[CH:24][C:19]([C:20]([O:22]C)=[O:21])=[CH:18][CH:17]=1)[CH:10]=[CH:9]2)([O-:5])=[O:4]>>[N+:3]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[N:11]([CH2:15][C:16]1[CH:25]=[CH:24][C:19]([C:20]([OH:22])=[O:21])=[CH:18][CH:17]=1)[CH:10]=[CH:9]2)([O-:5])=[O:4]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 68541319methyl 4-[(5-nitro-1H-indol-1-yl)methyl]benzoate

Product 1

HCID 592167084-[(5-Nitro-1H-indol-1-yl)methyl]benzoic acid

Procedure

4-[(5-Nitro-1H-indol-1-yl)methyl]benzoic acid was prepared by NaOH hydrolysis of methyl 4-[(5-nitro-1H-indol-1-yl)methyl]benzoate: MS (ESI) m/z 295;

Sources & evidence

ORD record
ord-447ced336f944199b0911342feb7962f
Source dataset
uspto-grants-2010_03
Patent number
US07683091B2

Reaction notes

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