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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2245518Generated: November 2, 2026

(1,1'-Biphenyl)-4-sulphonyl chloride → N-[4-({5-[(1,1'-Biphenyl-4-ylsulfonyl)amino]-1H-indol-1-yl}methyl)benzoyl]-L-phenylalanine

https://huagongshe.com/reaction/2245518

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-sulphonyl chlorideHCID 74192—
Reactantethyl N-{4-[(5-amino-1H-indol-1-yl)methyl]benzoyl}phenylalaninateHCID 68548160—
ProductN-[4-({5-[(1,1'-Biphenyl-4-ylsulfonyl)amino]-1H-indol-1-yl}methyl)benzoyl]-L-phenylalanineHCID 16113886—

Reaction Steps

The title compound was prepared from ethyl N-{4-[(5-amino-1H-indol-1-yl)methyl]benzoyl}phenylalaninate and biphenyl 4-sulfonyl chloride following the procedure of Example 10: MS (ESI) m/z 630; MS (ESI) m/z 628.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07683091B2
Source datasetuspto-grants-2010_03
ORD IDord-4b8097e105484474bc84c47f21ca449e
Source noteuspto-grants-2010_03