Potassium Hydroxide → (5-Nitro-1H-indol-1-yl)acetic acid

HRID 2245523Notes

Reaction equation

[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[N:9]([CH2:13][C:14]([O:16]C)=[O:15])[CH:8]=[CH:7]2)([O-:3])=[O:2].[OH-].[K+]>>[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[N:9]([CH2:13][C:14]([OH:16])=[O:15])[CH:8]=[CH:7]2)([O-:3])=[O:2]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 43152087HCID 43152087, compound

Product 1

HCID 21198561(5-Nitro-1H-indol-1-yl)acetic acid

Procedure

(5-Nitro-1H-indol-1-yl)acetic acid was prepared from methyl (5-nitro-1H-indol-1-yl)acetate by KOH hydrolysis: MS (ESI) m/z 219.

Sources & evidence

ORD record: ord-742eef1da46a436f986238a3276c8e29
Source dataset: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07683091B2

Reaction notes

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