Zincchloride → 3-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

HRID 224571Notes

Reaction equation

HRID 224571 reaction equation
[Cl-:1].[Zn+2:2].[Cl-].[N:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][O:11][C:12](=[S:22])[NH:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)[CH:5]=1>COCCO>[Cl-:1].[Zn+2:2].[C:20]([C:17]1[CH:18]=[CH:19][C:14]([NH:13][C:12](=[S:22])[O:11][CH2:10][C:6]2[CH:5]=[N:4][CH:9]=[CH:8][CH:7]=2)=[CH:15][CH:16]=1)#[N:21].[Cl-:1]

Participants

4

Reactant 2

HCID 3007855Zincchloride2×HCID 12790266O-[(Pyridin-3-yl)methyl] (4-cyanophenyl)carbamothioate

Product 1

HCID 867365583-pyridylmethyl N-(4-cyanophenyl)thiocarbamate zinc chloride

Reagents, catalysts & solvents 1

HCID 80192-MethoxyethanolSolvent2×

Procedure

The zinc chloride metal salt complex of Example I is made by dissolving 3-pyridylmethyl-N-(4-cyanophenyl)thiocarbamate (2.69 g., 0.01 mole) in 75 ml. of methyl cellosolve and adding to this stirred solution; a solution of zinc chloride (0.68 g., 0.005 mole) in 10 ml. of methyl cellosolve. The resulting solution is stirred at room temperature for 18 hours. The solvent is removed in vacuo and the residue is slurried in 30 ml. of methanol and collected on a filter to give 2.5 g. melting at 174°-5° C. with decomposition.

Workup

  1. customThe solvent is removed in vacuo
  2. customof methanol and collected on
  3. filtrationa filter
  4. customto give 2.5 g

Sources & evidence

ORD record
ord-9f2b28fa0cdf4290bfb269046261837d
Source dataset
uspto-grants-1980_11
Patent number
US04233289

Reaction notes

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