反应详情

To a solution of sorbic acid (1.12 g, 10 mmol) in dry methanol (50 mL) was added dropwise a solution of trimethylsilyl chloride (2M, 12 mL) in CH2Cl2. After stirring for 16 hours, the mixture was concentrated under reduced pressure to give a pale yellow oil that was purified by flash chromatography (9:1 60-80° C. petroleum ether:diethyl ether) to give the title compound (1.23 g, 99%) as a colourless oil.

1. concentrationthe mixture was concentrated under reduced pressure
2. customto give a pale yellow oil that
3. customwas purified by flash chromatography (9:1 60-80° C. petroleum ether:diethyl ether)