HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → HCID 178517796, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 6'-O-methyl alpha-amanitin | HCID 161349 | — |
| Reactant | HCID 178517701 | HCID 178517701 | — |
| Product | HCID 178517796 | HCID 178517796 | — |
Reaction Steps
Following a previously reported method (Meana A, et al, Synlett 2003, 1678-1682) compound 18 was prepared from N-iodosuccinimide (2.48 g, 11.0 mmol) and 3-bromo-2-hydroxypyridine 17 (1.74 g, 10.0 mmol) as a pale brown solid (2.55 g, 85%). 1H NMR (DMSO-d6) δ 12.27 (br s, 1H), 8.08 (d, 1H, J=2.3 Hz), 7.71 (d, 1H, J=2.3 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687052B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-49f6e5fee90d4809a47bf3945a47535d |
| Source note | uspto-grants-2010_03 |