Methanol → HCID 59217673, compound

Participants

Reaction Steps

13.5 g (0.04 mol) of 2-amino-3-(N-benzyl-N-formylamino)-3-phenylpropionic acid were dissolved in methanol, and 7.1 g (0.06 mol) of thionyl chloride and 1 drop of DMF were added dropwise. After 20 hours, the solvents were removed, the residue was suspended in diethyl ether and 5% strength NaHCO3 solution was added with stirring. The ether phase was separated off, washed and dried. Removal of the solvents gave 4.0 g of the title compound as a colorless oil which was used without further purification.

Provenance & Evidence