HCID 66916281, compound → HCID 68601405, compound

HRID 2246086Notes

Reaction equation

HRID 2246086 reaction equation
[C:1]([C:4]1[N:5]=[CH:6][S:7][C:8]=1/[CH:9]=[CH:10]\[S:11][C:12]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([OH:3])=O.C(C(C(C(O)=O)O)O)(O)=O.[OH:41][CH:42]1[CH2:45][NH:44][CH2:43]1>>[OH:41][CH:42]1[CH2:45][N:44]([C:1]([C:4]2[N:5]=[CH:6][S:7][C:8]=2/[CH:9]=[CH:10]\[S:11][C:12]([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)([C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[O:3])[CH2:43]1

Participants

3

Reactant 2

HCID 66916281HCID 66916281, compoundHCID 68601215HCID 68601215, compound

Product 1

HCID 68601405HCID 68601405, compoundYield 68.7%

Procedure

In the same manner as in step c) in Example 3, 0.742 g of the title compound was prepared from 0.957 g of 4-carboxy-5-((Z)-2-tritylthioethen-1-yl)thiazole and 0.757 g of 3-hydroxyazetidine tartrate.

Sources & evidence

ORD record
ord-271e1a9597a24e768b1c2e8f7dca43c7
Source dataset
uspto-grants-2010_03
Patent number
US07687490B2

Reaction notes

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