HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate → HCID 69471806, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate | HCID 23676797 | — |
| Reactant | Butyl iodomethyl carbonate | HCID 71428978 | — |
| Product | HCID 69471806 | HCID 69471806 | 100.5% |
Reaction Steps
In the same manner as in Example 81, 223 mg of the title compound was prepared from 175 mg of sodium (1R,5S,6S)-6-((1R)-1-hydroxyethyl)-2-[[(Z)-2-(4-hydroxymethylthiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate and 164 mg of (butan-1-yl)oxycarbonyloxymethyl iodide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687490B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-268a617b2d9c4c91a9ee33ee8886ba7e |
| Source note | uspto-grants-2010_03 |