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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2246124Generated: November 1, 2026

HCID 23449228, compound → HCID 69468651, compound

https://huagongshe.com/reaction/2246124

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23449228HCID 23449228—
ReactantSodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylateHCID 23676797—
ProductHCID 69468651HCID 6946865192.6%

Reaction Steps

In the same manner as in Example 81, 193 mg of the title compound was prepared from 160 mg of sodium (1R,5S,6S)-6-((1R)-1-hydroxyethyl)-2-[[(Z)-2-(4-hydroxymethylthiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate and 129 mg of neopentyloxycarbonyloxymethyl iodide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07687490B2
Source datasetuspto-grants-2010_03
ORD IDord-9f347b695d224d53bad763d96e6e0a58
Source noteuspto-grants-2010_03