HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate → HCID 69467710, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium (1r,5s,6s)-6-((1r)-1-hydroxyethyl)-2-[[(z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate | HCID 23676797 | — |
| Reactant | HCID 86609819 | HCID 86609819 | — |
| Product | HCID 69467710 | HCID 69467710 | 67.9% |
Reaction Steps
In the same manner as in step b) in Example 125, 279 mg of the title compound was prepared from 177 mg of chloromethyl N-isobutyl-N-isopropylcarbamate and 300 mg of sodium (1R,5S,6S)-6-((1R)-1-hydroxyethyl)-2-[[(Z)-2-(4-hydroxymethyl-thiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687490B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-6c244ee13a654fe1b2ae7a05c9dcba32 |
| Source note | uspto-grants-2010_03 |