反应详情

The process is performed as described in Example 1 (step 1.2.). Starting with 6 g (24.80 mmol) of 1-(5-bromo-2-pyridyl)piperazine, obtained in step 3.2., and 10.88 g (48.52 mmol) of ethyl [(phenyloxycarbonyl)oxy]acetate, prepared in step 1.1. of Example 1, and after chromatography on silica gel, eluting with a 15/85 and then 30/70 mixture of ethyl acetate and cyclohexane, 6.70 g of product are obtained in the form of an oil that crystallizes to a white solid.

1. customobtained in step 3.2
2. washof Example 1, and after chromatography on silica gel, eluting with a 15/85
3. addition30/70 mixture of ethyl acetate and cyclohexane, 6.70 g of product
4. customare obtained in the form of an oil that
5. customcrystallizes to a white solid