Benzo(d)thiazol-2-amine → HCID 11696808, compound

HRID 2246260Notes

Reaction equation

HRID 2246260 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9](I)[CH:10]=2)[N:5]=[CH:4][N:3]=1.[NH2:13][C:14]1[S:15][C:16]2[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=2[N:18]=1.[SH:23][C:24]1[N:28]([CH3:29])[CH:27]=[N:26][N:25]=1>>[S:15]1[C:16]2[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=2[N:18]=[C:14]1[NH:13][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([S:23][C:24]3[N:28]([CH3:29])[CH:27]=[N:26][N:25]=3)[CH:10]=2)[N:5]=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 8706Benzo(d)thiazol-2-amineHCID 111738094-Chloro-6-iodoquinazolineHCID 178481306HCID 178481306, compound

Product 1

HCID 11696808HCID 11696808, compound

Procedure

The compound of Example 15 was manufactured by the same method as in Example 1, by a similar method thereto or by a combination of such a method with a conventional method using 4-chloro-6-iodo-quinazoline, 2-amino-benzothiazole and 3-mercapto-4-methyl-1,2,4-triazole.

Sources & evidence

ORD record
ord-c6fa0bc2e36b4fcf942ac4012ec3ed58
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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