[1,3]Thiazolo[5,4-b]pyridin-2-amine → HCID 11668332, compound

HRID 2246276Notes

Reaction equation

HRID 2246276 reaction equation
Cl[C:2]1[C:3]2[N:11]=[C:10](Cl)[CH:9]=[CH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[N:13]1[C:21]2[C:16](=[N:17][CH:18]=[CH:19][CH:20]=2)[S:15][C:14]=1[NH2:22].[SH:23][C:24]1[N:28]([CH3:29])[CH:27]=[N:26][N:25]=1>>[CH3:29][N:28]1[CH:27]=[N:26][N:25]=[C:24]1[S:23][C:10]1[CH:9]=[CH:8][C:4]2[N:5]=[CH:6][N:7]=[C:2]([NH:22][C:14]3[S:15][C:16]4[C:21]([N:13]=3)=[CH:20][CH:19]=[CH:18][N:17]=4)[C:3]=2[N:11]=1

Participants

4

Reactant 3

HCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178481306HCID 178481306, compound

Product 1

HCID 11668332HCID 11668332, compound

Procedure

The compound of Example 34 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 4,6-dichloro-pyrido[3,2-d]pyrimidine, thiazolo[5,4-b]-pyridin-2-yl-amine and 3-mercapto-4-methyl-1,2,4-triazole.

Sources & evidence

ORD record
ord-4141f3ecb5d947b899b824ef51f7acb9
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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