[1,3]Thiazolo[5,4-b]pyridin-2-amine → HCID 178434143, compound

HRID 2246277Notes

Reaction equation

HRID 2246277 reaction equation
Cl[C:2]1[C:3]2[N:11]=[C:10](Cl)[CH:9]=[CH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[N:13]1[C:21]2[C:16](=[N:17][CH:18]=[CH:19][CH:20]=2)[S:15][C:14]=1[NH2:22].[SH:23][C:24]1[N:28]=[C:27]([CH3:29])[NH:26][N:25]=1>>[CH3:29][C:27]1[NH:28][C:24]([S:23][C:10]2[CH:9]=[CH:8][C:4]3[N:5]=[CH:6][N:7]=[C:2]([NH:22][C:14]4[S:15][C:16]5[C:21]([N:13]=4)=[CH:20][CH:19]=[CH:18][N:17]=5)[C:3]=3[N:11]=2)=[N:25][N:26]=1

Participants

4

Reactant 3

HCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 1784335565-methyl-1H-1,2,4-triazole-3-thiol

Product 1

HCID 178434143HCID 178434143, compound

Procedure

The compound of Example 35 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 4,6-dichloro-pyrido[3,2-d]pyrimidine, thiazolo[5,4-b]-pyridin-2-yl-amine and 3-mercapto-5-methyl-1,2,4-triazole.

Sources & evidence

ORD record
ord-10fb18a33a5a49688654432b7669c465
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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