Ethanolamine → HCID 23331662, compound

HRID 224628Notes

Reaction equation

HRID 224628 reaction equation
Cl[C:2]1[C:7]2[C:8]([CH3:17])=[N:9][C:10]3[N:14]([CH2:15][CH3:16])[N:13]=[CH:12][C:11]=3[C:6]=2[N:5]2[N:18]=[C:19]([CH3:21])[CH:20]=[C:4]2[N:3]=1.[CH2:22]([CH2:24][NH2:25])[OH:23].CN(C)CCCO>>[NH2:25][CH2:24][CH2:22][O:23][C:2]1[C:7]2[C:8]([CH3:17])=[N:9][C:10]3[N:14]([CH2:15][CH3:16])[N:13]=[CH:12][C:11]=3[C:6]=2[N:5]2[N:18]=[C:19]([CH3:21])[CH:20]=[C:4]2[N:3]=1

Participants

4

Reactant 3

HCID 700EthanolamineHCID 766463-(Dimethylamino)-1-propanolHCID 23331618HCID 23331618, compound

Product 1

HCID 23331662HCID 23331662, compound

Procedure

By substituting the 5-chloro-2,6-dimethyl-8-ethyl-8H pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidine obtained in Example 37 in the procedure of Example 21 and substituting ethanolamine for the 3-(dimethylamino)propanol, 5-(2-aminoethoxy)-2,6-dimethyl-8-ethyl-8H-pyrazolo[1,5-a]-pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidine is obtained.

Sources & evidence

ORD record
ord-d41eca7d37574b13b70fc72397376557
Source dataset
uspto-grants-1980_11
Patent number
US04233300

Reaction notes

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