[1,3]Thiazolo[5,4-b]pyridin-2-amine → HCID 23160332, compound

HRID 2246280Notes

Reaction equation

HRID 2246280 reaction equation
[SH:1][C:2]1[CH:6]=[CH:5][N:4]([CH3:7])[N:3]=1.[N:8]1[C:16]2[C:11](=[N:12][CH:13]=[CH:14][CH:15]=2)[S:10][C:9]=1[NH2:17].Cl[C:19]1[C:20]2[N:28]=[C:27](Cl)[CH:26]=[CH:25][C:21]=2[N:22]=[CH:23][N:24]=1>>[CH3:7][N:4]1[CH:5]=[CH:6][C:2]([S:1][C:14]2[CH:15]=[C:16]3[N:8]=[C:9]([NH:17][C:19]4[C:20]5[N:28]=[CH:27][CH:26]=[CH:25][C:21]=5[N:22]=[CH:23][N:24]=4)[S:10][C:11]3=[N:12][CH:13]=2)=[N:3]1

Participants

4

Reactant 3

HCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178480547HCID 178480547, compound

Product 1

HCID 23160332HCID 23160332, compound

Procedure

The compound of Example 39 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 3-mercapto-1-methylpyrazole, thiazolo[5,4-b]pyridin-2-yl-amine and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-5b3203ac3bfd4092b6dd1433f3b90874
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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