[1,3]Thiazolo[5,4-b]pyridin-2-amine → HCID 23160301, compound

HRID 2246281Notes

Reaction equation

HRID 2246281 reaction equation
[SH:1][C:2]1[N:6]=[C:5]([CH2:7][O:8][CH3:9])[NH:4][N:3]=1.Cl[C:11]1[C:12]2[N:20]=[C:19](Cl)[CH:18]=[CH:17][C:13]=2[N:14]=[CH:15][N:16]=1.[N:22]1[C:30]2[C:25](=[N:26][CH:27]=[CH:28][CH:29]=2)[S:24][C:23]=1[NH2:31]>>[CH3:9][O:8][CH2:7][C:5]1[NH:4][N:3]=[C:2]([S:1][N:31]([C:23]2[S:24][C:25]3[C:30]([N:22]=2)=[CH:29][CH:28]=[CH:27][N:26]=3)[C:11]2[C:12]3[N:20]=[CH:19][CH:18]=[CH:17][C:13]=3[N:14]=[CH:15][N:16]=2)[N:6]=1

Participants

4

Reactant 3

HCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178494705HCID 178494705, compound

Product 1

HCID 23160301HCID 23160301, compound

Procedure

The compound of Example 41 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 3-mercapto-5-methoxymethyl[1,2,4]triazole, 4,6-dichloro-pyrido-[3,2-d]pyrimidine and thiazolo[5,4-b]pyridin-2-yl-amine.

Sources & evidence

ORD record
ord-8940adc924bc41d8af24b352b588cf60
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

Loading…