5-Methylpyrazin-2-amine → HCID 11588059, compound

HRID 2246284Notes

Reaction equation

HRID 2246284 reaction equation
[SH:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.[NH2:7][C:8]1[CH:13]=[N:12][C:11]([CH3:14])=[CH:10][N:9]=1.Cl[C:16]1[C:17]2[N:25]=[C:24](Cl)[CH:23]=[CH:22][C:18]=2[N:19]=[CH:20][N:21]=1>>[NH:3]1[CH:4]=[CH:5][N:6]=[C:2]1[S:1][C:24]1[CH:23]=[CH:22][C:18]2[N:19]=[CH:20][N:21]=[C:16]([NH:7][C:8]3[CH:13]=[N:12][C:11]([CH3:14])=[CH:10][N:9]=3)[C:17]=2[N:25]=1

Participants

4

Reactant 3

HCID 3132155-Methylpyrazin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178527877HCID 178527877, compound

Product 1

HCID 11588059HCID 11588059, compound

Procedure

The compound of Example 44 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 2-mercaptoimidazole, 2-amino-5-methylpyrazine and 4,6-dichloropyrido-[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-c367ffb19dd2436dbf8e8a2f5c4a2232
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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