HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methylpyrazin-2-amine → 6-(1-Ethylimidazol-2-yl-sulfanyl)-(5-methylpyrazin-2-yl)-pyrido[3,2-d]pyrimidin-4-yl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methylpyrazin-2-amine | HCID 313215 | — |
| Reactant | 4,6-Dichloropyrido[3,2-d]pyrimidine | HCID 10584165 | — |
| Reactant | 1-ethyl-1H-imidazole-2-thiol | HCID 178462645 | — |
| Product | 6-(1-Ethylimidazol-2-yl-sulfanyl)-(5-methylpyrazin-2-yl)-pyrido[3,2-d]pyrimidin-4-yl-amine | HCID 11595715 | — |
Reaction Steps
The compound of Example 45 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 1-ethyl-2-mercaptoimidazole, 2-amino-5-methylpyrazine and 4,6-dichloropyrido-[3,2-d]pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687502B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-752e017d66fd401d949209b98396e332 |
| Source note | uspto-grants-2010_03 |