5-Methylpyrazin-2-amine → HCID 11667712, compound

HRID 2246287Notes

Reaction equation

HRID 2246287 reaction equation
[SH:1][C:2]1[N:3]([CH3:8])[C:4]([CH3:7])=[CH:5][N:6]=1.[NH2:9][C:10]1[CH:15]=[N:14][C:13]([CH3:16])=[CH:12][N:11]=1.Cl[C:18]1[C:19]2[N:27]=[C:26](Cl)[CH:25]=[CH:24][C:20]=2[N:21]=[CH:22][N:23]=1>>[CH3:8][N:3]1[C:4]([CH3:7])=[CH:5][N:6]=[C:2]1[S:1][C:26]1[CH:25]=[CH:24][C:20]2[N:21]=[CH:22][N:23]=[C:18]([NH:9][C:10]3[CH:15]=[N:14][C:13]([CH3:16])=[CH:12][N:11]=3)[C:19]=2[N:27]=1

Participants

4

Reactant 3

HCID 3132155-Methylpyrazin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178430801HCID 178430801, compound

Product 1

HCID 11667712HCID 11667712, compound

Procedure

The compound of Example 47 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 2-mercapto-1,5-dimethylimidazole, 2-amino-5-methylpyrazine and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-ad32fe1b24c245e8ae361e696302864e
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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