[1,3]Thiazolo[5,4-b]pyridin-2-amine → HCID 11654123, compound

HRID 2246290Notes

Reaction equation

HRID 2246290 reaction equation
[SH:1][C:2]1[S:3][CH:4]=[N:5][N:6]=1.[N:7]1[C:15]2[C:10](=[N:11][CH:12]=[CH:13][CH:14]=2)[S:9][C:8]=1[NH2:16].Cl[C:18]1[C:19]2[N:27]=[C:26](Cl)[CH:25]=[CH:24][C:20]=2[N:21]=[CH:22][N:23]=1>>[S:3]1[CH:4]=[N:5][N:6]=[C:2]1[S:1][C:26]1[CH:25]=[CH:24][C:20]2[N:21]=[CH:22][N:23]=[C:18]([NH:16][C:8]3[S:9][C:10]4[C:15]([N:7]=3)=[CH:14][CH:13]=[CH:12][N:11]=4)[C:19]=2[N:27]=1

Participants

4

Reactant 3

HCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178527973HCID 178527973, compound

Product 1

HCID 11654123HCID 11654123, compound

Procedure

The compound of Example 52 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 2-mercapto-[1,3,4]thiadiazole, thiazolo[5,4-b]pyridin-2-yl-amine and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-9d358b72a1f848ba90806132e014d86d
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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