[1,3]Thiazolo[5,4-b]pyridin-2-amine → HCID 11581976, compound

HRID 2246291Notes

Reaction equation

HRID 2246291 reaction equation
[SH:1][C:2]1[N:6]([CH3:7])[N:5]=[N:4][N:3]=1.[N:8]1[C:16]2[C:11](=[N:12][CH:13]=[CH:14][CH:15]=2)[S:10][C:9]=1[NH2:17].Cl[C:19]1[C:20]2[N:28]=[C:27](Cl)[CH:26]=[CH:25][C:21]=2[N:22]=[CH:23][N:24]=1>>[CH3:7][N:6]1[C:2]([S:1][C:27]2[CH:26]=[CH:25][C:21]3[N:22]=[CH:23][N:24]=[C:19]([NH:17][C:9]4[S:10][C:11]5[C:16]([N:8]=4)=[CH:15][CH:14]=[CH:13][N:12]=5)[C:20]=3[N:28]=2)=[N:3][N:4]=[N:5]1

Participants

4

Reactant 3

HCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amineHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178482017HCID 178482017, compound

Product 1

HCID 11581976HCID 11581976, compound

Procedure

The compound of Example 53 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 5-mercapto-1-methyl-1H-tetrazole, thiazolo[5,4-b]pyridin-2-yl-amine and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-7395103dda074c6e829ba358f4365522
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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