1-Methyl-3-aminopyrazole → HCID 178480442, compound

HRID 2246293Notes

Reaction equation

HRID 2246293 reaction equation
[SH:1][C:2]1[NH:3][N:4]=[N:5][CH:6]=1.[NH2:7][C:8]1[CH:12]=[CH:11][N:10]([CH3:13])[N:9]=1.Cl[C:15]1[C:16]2[N:24]=[C:23](Cl)[CH:22]=[CH:21][C:17]=2[N:18]=[CH:19][N:20]=1>>[N:5]1[CH:6]=[C:2]([S:1][C:23]2[CH:22]=[CH:21][C:17]3[N:18]=[CH:19][N:20]=[C:15]([NH:7][C:8]4[CH:12]=[CH:11][N:10]([CH3:13])[N:9]=4)[C:16]=3[N:24]=2)[NH:3][N:4]=1

Participants

4

Reactant 3

HCID 1372541-Methyl-3-aminopyrazoleHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178527741HCID 178527741, compound

Product 1

HCID 178480442HCID 178480442, compound

Procedure

The compound of Example 57 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 4-mercapto-3H-[1,2,3]triazole, 3-amino-1-methyl-1H-pyrazole and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-4a4e135cf7de4cf9aad6993fbc6accb5
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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