1-Methyl-3-aminopyrazole → HCID 178434142, compound

HRID 2246294Notes

Reaction equation

HRID 2246294 reaction equation
[SH:1][C:2]1[NH:6][C:5]([CH3:7])=[N:4][N:3]=1.[NH2:8][C:9]1[CH:13]=[CH:12][N:11]([CH3:14])[N:10]=1.Cl[C:16]1[C:17]2[N:25]=[C:24](Cl)[CH:23]=[CH:22][C:18]=2[N:19]=[CH:20][N:21]=1>>[CH3:7][C:5]1[NH:6][C:2]([S:1][C:24]2[CH:23]=[CH:22][C:18]3[N:19]=[CH:20][N:21]=[C:16]([NH:8][C:9]4[CH:13]=[CH:12][N:11]([CH3:14])[N:10]=4)[C:17]=3[N:25]=2)=[N:3][N:4]=1

Participants

4

Reactant 3

HCID 1372541-Methyl-3-aminopyrazoleHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178434157HCID 178434157, compound

Product 1

HCID 178434142HCID 178434142, compound

Procedure

The compound of Example 58 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 3-mercapto-5-methyl-4H-[1,2,4]triazole, 3-amino-1-methyl-1H-pyrazole and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-e31ba95cd0ea40cd9f0bc9d27ed83a61
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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