1-Methyl-3-aminopyrazole → HCID 11545172, compound

HRID 2246295Notes

Reaction equation

HRID 2246295 reaction equation
[Cl:1][C:2]1[C:3]([SH:8])=[N:4][CH:5]=[CH:6][CH:7]=1.[NH2:9][C:10]1[CH:14]=[CH:13][N:12]([CH3:15])[N:11]=1.Cl[C:17]1[C:18]2[N:26]=[C:25](Cl)[CH:24]=[CH:23][C:19]=2[N:20]=[CH:21][N:22]=1>>[Cl:1][C:2]1[C:3]([S:8][C:25]2[CH:24]=[CH:23][C:19]3[N:20]=[CH:21][N:22]=[C:17]([NH:9][C:10]4[CH:14]=[CH:13][N:12]([CH3:15])[N:11]=4)[C:18]=3[N:26]=2)=[N:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 1372541-Methyl-3-aminopyrazoleHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178527858HCID 178527858, compound

Product 1

HCID 11545172HCID 11545172, compound

Procedure

The compound of Example 59 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 3-chloro-2-mercapto-pyridine, 3-amino-1-methyl-1H-pyrazole and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Sources & evidence

ORD record
ord-e786bc878e4f45328d67700ca0997e47
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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