1-Methyl-3-aminopyrazole → HCID 11508935, compound

HRID 2246301Notes

Reaction equation

HRID 2246301 reaction equation
[Cl:1][C:2]1[C:3]([SH:8])=[N:4][CH:5]=[CH:6][CH:7]=1.[NH2:9][C:10]1[CH:14]=[CH:13][N:12]([CH3:15])[N:11]=1.Cl[C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[C:24](I)[CH:25]=2)[N:20]=[CH:19][N:18]=1>>[Cl:1][C:2]1[C:3]([S:8][C:24]2[CH:25]=[C:26]3[C:21](=[CH:22][CH:23]=2)[N:20]=[CH:19][N:18]=[C:17]3[NH:9][C:10]2[CH:14]=[CH:13][N:12]([CH3:15])[N:11]=2)=[N:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 1372541-Methyl-3-aminopyrazoleHCID 111738094-Chloro-6-iodoquinazolineHCID 178527858HCID 178527858, compound

Product 1

HCID 11508935HCID 11508935, compound

Procedure

The compound of Example 74 was manufactured by the same method as in Example 1, by a similar method thereto or by a combination of such a method with a conventional method using 3-chloro-2-mercapto-pyridine, 3-amino-1-methylpyrazole and 4-chloro-6-iodoquinazoline.

Sources & evidence

ORD record
ord-2a7f707b3154474dacffbc7ec46f1697
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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