2,3-Dichloropyridine → HCID 11495171, compound

HRID 2246302Notes

Reaction equation

HRID 2246302 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][N:3]=1.[N:9]1[C:17]2[C:12](=[N:13][CH:14]=[CH:15][CH:16]=2)[S:11][C:10]=1[NH2:18].Cl[C:20]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([OH:30])[CH:28]=2)[N:23]=[CH:22][N:21]=1>>[Cl:8][C:7]1[C:2]([O:30][C:27]2[CH:28]=[C:29]3[C:24](=[CH:25][CH:26]=2)[N:23]=[CH:22][N:21]=[C:20]3[NH:18][C:10]2[S:11][C:12]3[C:17]([N:9]=2)=[CH:16][CH:15]=[CH:14][N:13]=3)=[N:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 169882,3-DichloropyridineHCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amineHCID 231602734-Chloroquinazolin-6-ol

Product 1

HCID 11495171HCID 11495171, compound

Procedure

The compound of Example 79 was manufactured by the same method as in Example 95, by a similar method thereto or by a combination of such a method with a conventional method using 2,3-dichloropyridine, thiazolo[5,4-b]pyridin-2-yl-amine and 4-chloro-6-hydroxy-quinazoline.

Sources & evidence

ORD record
ord-e2641c15a95b452fbc8f31e7a9f41f9d
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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