2,3-Dichloropyridine → HCID 11624898, compound

HRID 2246307Notes

Reaction equation

HRID 2246307 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][N:3]=1.[NH2:9][C:10]1[S:14][N:13]=[C:12]([CH3:15])[N:11]=1.Cl[C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[C:24]([OH:27])[CH:25]=2)[N:20]=[CH:19][N:18]=1>>[Cl:8][C:7]1[C:2]([O:27][C:24]2[CH:25]=[C:26]3[C:21](=[CH:22][CH:23]=2)[N:20]=[CH:19][N:18]=[C:17]3[NH:9][C:10]2[S:14][N:13]=[C:12]([CH3:15])[N:11]=2)=[N:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 169882,3-DichloropyridineHCID 3506395-Amino-3-methyl-1,2,4-thiadiazoleHCID 231602734-Chloroquinazolin-6-ol

Product 1

HCID 11624898HCID 11624898, compound

Procedure

The compound of Example 86 was manufactured by the same method as in Example 95, by a similar method thereto or by a combination of such a method with a conventional method using 2,3-dichloropyridine, 5-amino-3-methyl-[1,2,4]thiadiazole and 4-chloro-6-hydroxy-quinazoline.

Sources & evidence

ORD record
ord-c4823e6d1dbf433780a5f6053edcc30a
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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