3(2H)-Pyridazinone, 4,5-dichloro-2-methyl- → HCID 23160264, compound

HRID 2246334Notes

Reaction equation

HRID 2246334 reaction equation
Cl[C:2]1[C:3](=[O:10])[N:4]([CH3:9])[N:5]=[CH:6][C:7]=1[Cl:8].[NH2:11][C:12]1[CH:16]=[CH:15][N:14]([CH3:17])[N:13]=1.Cl[C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[C:26]([OH:29])[CH:27]=2)[N:22]=[CH:21][N:20]=1>>[Cl:8][C:7]1[CH:6]=[N:5][N:4]([CH3:9])[C:3](=[O:10])[C:2]=1[O:29][C:26]1[CH:27]=[C:28]2[C:23](=[CH:24][CH:25]=1)[N:22]=[CH:21][N:20]=[C:19]2[NH:11][C:12]1[CH:16]=[CH:15][N:14]([CH3:17])[N:13]=1

Participants

4

Reactant 3

HCID 1204623(2H)-Pyridazinone, 4,5-dichloro-2-methyl-HCID 1372541-Methyl-3-aminopyrazoleHCID 231602734-Chloroquinazolin-6-ol

Product 1

HCID 23160264HCID 23160264, compound

Procedure

The compound of Example 127 was manufactured by the same method as in Example 95, by a similar method thereto or by a combination of such a method with a conventional method using 4,5-dichloro-2-methyl-3(2H)pyridazinone, 3-amino-1-methyl-1H-pyrazole and 4-chloro-6-hydroxy-quinazoline.

Sources & evidence

ORD record
ord-e0d1ee0d8e44415582a3142df6056dd3
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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