HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic acid dihydrate → N,N-dimethyl-3-[3-[(1-methylthio-2-nitroethenyl)amino]propoxy]benzenemethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic acid dihydrate | HCID 61373 | — |
| Reactant | 1,1-Bis(methylsulfanyl)-2-nitroethane | HCID 12372264 | — |
| Reactant | 3-(3-Aminopropoxy)-N,N-dimethylbenzenemethanamine | HCID 12913950 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N,N-dimethyl-3-[3-[(1-methylthio-2-nitroethenyl)amino]propoxy]benzenemethanamine | HCID 70538402 | 64% |
Reaction Steps
3-(3-Aminopropoxy)-N,N-dimethylbenzenemethanamine (10 g) and 1,1-bis-(methylthio)-2-nitroethane (16 g) were heated under reflux in tetrahydrofuran for 19 hours. Oxalic acid dihydrate (1.3 g) was added and the resulting precipitate was discarded. The solvent was removed to leave the title compound as a crystalline solid (10 g) m.p. 59°-63°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04233302 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-0168655c41f94fc4b8df7f4e22af38e2 |
| Source note | uspto-grants-1980_11 |