HCID 58938125, compound → HCID 58938115, compound

Participants

Reaction Steps

To a stirring suspension of 4-amino-3-nitro-6-(3-trifluoromethyl-phenyl)-pyridine-2-carbonitrile (300 mg, 0.97 mmol) in ethyl acetate (80 ml) was added 10% palladium on carbon (wet) (300 mg, 2.82 mmol). The vessel was purged with hydrogen (balloon) and stirred at room temperature for 1.5 hrs. Reaction mixture was filtered through celite and concentrated in vacuo to give the title compound as a dark orange solid (240 mg, 89%). 1H NMR (MeOD): δ 8.15 (s, 1H), 8.04 (d, 1H), 7.58-7.65 (m, 2H), 7.18 (s, 1H). MS m/z 279.3 (M+1).

Provenance & Evidence