Acetic Acid → HCID 86605975, compound

Participants

Reaction Steps

2.02 mL of a 1 M solution of tetrabutylammonium fluoride in tetrahydrofuran are added to a solution of 1.3 g 1-methyl-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos1-yl)-2-[4-(tert-butyl-dimethyl-silyloxy)-benzyl]-benzene and 0.12 mL acetic acid in 10 mL of tetrahydrofuran. The solution is stirred for 30 min at ambient temperature, and then 50 mL ethyl acetate and 10 mL water are added. The organic layer is separated, washed with aqueous NaHCO3 solution, and dried over MgSO4. After removal of the solvent, the residue is recrystallized from a mixture of ethyl acetate and petrol ether.

Provenance & Evidence