Phenyl isocyanate → HCID 25261084, compound

HRID 2246542Notes

Reaction equation

FC(F)(F)C([O-])=O.[C:8]([O:11][C@@:12]1([CH2:44][CH3:45])[C:17]2[CH:18]=[C:19]3[N:27]([C:28](=[O:29])[C:16]=2[CH2:15][O:14][C:13]1=[O:43])[CH2:26][C:25]1[C:24]([CH2:30][CH2:31][Si:32]([CH3:38])([CH3:37])[CH2:33][CH2:34][CH2:35][NH3+:36])=[C:23]2[CH:39]=[CH:40][CH:41]=[CH:42][C:22]2=[N:21][C:20]3=1)(=[O:10])[CH3:9].[C:46]1([N:52]=[C:53]=[O:54])[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=1>>[CH3:38][Si:32]([CH3:37])([CH2:33][CH2:34][CH2:35][NH:36][C:53]([NH:52][C:46]1[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=1)=[O:54])[CH2:31][CH2:30][C:24]1[C:25]2[CH2:26][N:27]3[C:19](=[CH:18][C:17]4[C@@:12]([O:11][C:8](=[O:10])[CH3:9])([CH2:44][CH3:45])[C:13](=[O:43])[O:14][CH2:15][C:16]=4[C:28]3=[O:29])[C:20]=2[N:21]=[C:22]2[CH:42]=[CH:41][CH:40]=[CH:39][C:23]=12

Participants

Reactant 2

HCID 7672Phenyl isocyanate

HCID 68530477HCID 68530477, compound

Product 1

HCID 25261084HCID 25261084, compound

Procedure

The required product was prepared according to Procedure E, above, using Compound 21 and phenyl isocyanate. The required product was obtained in 50% yield.

Workup

customThe required product was prepared

Sources & evidence

ORD record: ord-9569ec3d8cf7413a890ffe716ff280fa
Source dataset: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07687496B2

Reaction notes

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