HCID 12603260, compound → HCID 56615012, compound

HRID 224660Notes

Reaction equation

HRID 224660 reaction equation
C(OC[C@@H](N1C(C)=CC=C1C)C)(=O)C.[C:15]([O:18][CH2:19][CH:20]([N:22]1[C:26]([CH3:27])=[CH:25][C:24]([C:28](=[O:35])[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[C:23]1[CH3:36])[CH3:21])(=[O:17])[CH3:16]>>[C:15]([O:18][CH2:19][C@@H:20]([N:22]1[C:26]([CH3:27])=[CH:25][C:24]([C:28](=[O:35])[C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)=[C:23]1[CH3:36])[CH3:21])(=[O:17])[CH3:16]

Participants

3

Reactant 2

HCID 12603260HCID 12603260, compoundHCID 22812933HCID 22812933, compound

Product 1

HCID 56615012HCID 56615012, compoundYield 42.8%

Procedure

Compound (316) was prepared in a yield of 42.8% using (2S)-2-(2,5-dimethylpyrrol-1-yl)-2 methylethyl acetate ([α]D21 =-5.17°, c=0.027, C2H5OH) as a starting material in the same way as in Example 28. The IR, NMR and mass spectra of this product were identical with those of the product (306) of Example 28.

Sources & evidence

ORD record
ord-92aae33133b04737be75dc731adc8111
Source dataset
uspto-grants-1980_11
Patent number
US04233309

Reaction notes

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