HCID 86618162, compound → HCID 86618165, compound

Participants

Reaction Steps

A sample of the product from Step 5 was dissolved in MeOH (100 ml). Palladium on carbon (0.185 g, 1.743 mmol) was added to the solution and the reaction mixture was stirred under 50 psi hydrogen for 2 h. The reaction mixture was filtered through Celite with EtOAc. The resulting solution was concentrated in vacuo to yield tert-butyl ((1S,2S,5R)-2-amino-5-methoxycyclohexyl)methylcarbamate as a clear oil which was used without any further purification. A quantitative yield was assumed. LC/MS found [M+H]+=259.41.

Provenance & Evidence