m-Chloroperbenzoic acid → HCID 23331770, compound

Participants

Reaction Steps

In 15 ml of methylene chloride was dissolved 589 mg (1.76 mmoles) of 2-(3-benzoyl-2,5-dimethylpyrrol-1-yl)ethyl phenyl sulfide, and 350 mg (1.72 mmoles) of m-chloroperbenzoic acid (85% purity) was added. The mixture was stirred at room temperature for 16 hours. The organic layer was washed with a 1.0 N aqueous solution of sodium hydroxide, and then water, dried, and concentrated, and chromatographed on a column of silic gel using benzene/ethyl acetate as an eluent to afford compound (410)(562 mg, 1.60 mmoles, 91%).

Provenance & Evidence