Diethyl Ether → HCID 23331799, compound

Participants

Reaction Steps

Ethyl orthoformate (2 ml) and one drop of conc. sulfuric acid were added to 257 mg (1.0 mmole) of 2-(3-benzoyl-2,5-dimethylpyrrol-1-yl)propionaldehyde, and the reaction was performed at room temperature for 5 hours. Ether was added, and the organic layer was washed with water, dried, concentrated and chromatographed on a column of silica gel to afford compound (904) (82 mg, 0.25 mmole, 25%).

Provenance & Evidence