o-Chlorothiophenol → HCID 11429179, compound

HRID 2246713Notes

Reaction equation

HRID 2246713 reaction equation
[C:1]([NH:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[C:7]([S:19]C1C=CC=C(Cl)C=1)=[C:8]([CH3:18])[N:9]2[CH2:14][C:15]([OH:17])=[O:16])(=[O:3])[CH3:2].[Cl:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=1S>>[C:1]([NH:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[C:7]([S:19][C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][C:28]=1[Cl:27])=[C:8]([CH3:18])[N:9]2[CH2:14][C:15]([OH:17])=[O:16])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 80599o-ChlorothiophenolHCID 11349765HCID 11349765, compound

Product 1

HCID 11429179HCID 11429179, compound

Procedure

The title compound was prepared by the method of Example 5 parts (iv) and using the product from Example 17 part (i) and 2-chlorothiophenol, and purified by column chromatography (33% EtOAc/hexane as eluent). The resulting product was treated as outlined in example 1 part (v) to give the title compound.

Workup

  1. custompurified by column chromatography (33% EtOAc/hexane as eluent)
  2. additionThe resulting product was treated

Sources & evidence

ORD record
ord-7b7b9196a4ef4d3d88c86f9fa1dba0ca
Source dataset
uspto-grants-2010_03
Patent number
US07687535B2

Reaction notes

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