HCID 11349765, compound → HCID 11190053, compound

HRID 2246714Notes

Reaction equation

HRID 2246714 reaction equation
[C:1]([NH:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[C:7]([S:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22](Cl)[CH:21]=1)=[C:8]([CH3:18])[N:9]2[CH2:14][C:15]([OH:17])=[O:16])(=[O:3])[CH3:2].[CH2:27]([S:29](C1C=CC(S)=CC=1)(=[O:31])=[O:30])[CH3:28]>>[C:1]([NH:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[C:7]([S:19][C:20]1[CH:25]=[CH:24][C:23]([S:29]([CH2:27][CH3:28])(=[O:31])=[O:30])=[CH:22][CH:21]=1)=[C:8]([CH3:18])[N:9]2[CH2:14][C:15]([OH:17])=[O:16])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 11349765HCID 11349765, compoundHCID 19902355HCID 19902355, compound

Product 1

HCID 11190053HCID 11190053, compound

Procedure

The title compound was prepared by the method of Example 5 part (iv) using the product from Example 17 part (i) and 4-(ethylsulfonyl)benzenethiol. The product was purified by preparative hplc (eluent MeCN/NH3 (aq)).

Workup

  1. customThe product was purified by preparative hplc (eluent MeCN/NH3 (aq))

Sources & evidence

ORD record
ord-fcb06269c15a4b92b568c633328c89ea
Source dataset
uspto-grants-2010_03
Patent number
US07687535B2

Reaction notes

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