2-Mercaptobenzoic Acid → HCID 68691641, compound

Participants

Reaction Steps

Thiosalicylic acid (0.35 g) was added to a solution of the product from Example 2 part (i) (0.47 g) in TFA (10 ml). The mixture was stirred at room temperature for 1 hour and then heated at 60° C. for 4 hours. The TFA was evaporated and the residue dissolved in EtOAc. The organics were washed with aqueous sodium bicarbonate and brine, died (MgSO4) and evaporated. The residue was purified using chromatography (50% EtOAc/hexane as eluent) to give the sub-title compound (0.16 g).

Provenance & Evidence