Calcium → HCID 70503069, compound

HRID 224675Notes

Reaction equation

HRID 224675 reaction equation
[Ca:1].[CH3:2][C:3]1[S:10][C:9]2[S:8](=[O:12])(=[O:11])[NH:7][C:6](=[O:13])[C:5]=2[CH:4]=1>CO>[Ca:1].[CH3:2][C:3]1[S:10][C:9]2[S:8](=[O:12])(=[O:11])[NH:7][C:6](=[O:13])[C:5]=2[CH:4]=1

Participants

4

Reactant 2

HCID 5460341CalciumHCID 13869332HCID 13869332, compound

Product 1

HCID 70503069HCID 70503069, compoundYield 130.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

500 ml of methanol were added to 0.49 gm (12.3 millimols) of calcium, the mixture was refluxed, and 5.0 gm (24.6 millimols) of 5-methyl-thieno[3,2-d]isothiazole-3(2H)-one-1,1-dioxide were added to the suspension thus obtained. The resulting solution was evaporated, and the residue was recrystallized from a little ethanol/ether. 3.9 gm (71% of theory) of 5-methyl-thieno[3,2-d]-isothiazole-3(2H)-one-1,1-dioxide calcium salt were obtained.

Workup

  1. temperaturethe mixture was refluxed
  2. customthus obtained
  3. customThe resulting solution was evaporated
  4. customthe residue was recrystallized from a little ethanol/ether

Sources & evidence

ORD record
ord-f34841565b8b4e83b95dc1702c933102
Source dataset
uspto-grants-1980_11
Patent number
US04233333

Reaction notes

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