4-Aminobenzophenone → HCID 17982605, compound

HRID 2246810Notes

Reaction equation

[NH2:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[Cl:16][C:17]1(Cl)[CH2:22][O:21][CH2:20][CH2:19][O:18]1>>[C:6]([C:5]1[CH:4]=[CH:3][C:2]([NH:1][C:19](=[O:18])[CH2:20][O:21][CH2:22][CH2:17][Cl:16])=[CH:15][CH:14]=1)(=[O:7])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

Reactant 2

HCID 143464-Aminobenzophenone

HCID 124243252,2-Dichloro-1,4-dioxane

Product 1

HCID 17982605HCID 17982605, compound

Conditions

Temperature: 80 °C

Procedure

A mixture of 1.60 g (8.12 mmol) of 4-aminobenzophenone and 1.11 g of 2-chlorodioxene (contains 6% of 2,2-dichlorodioxane) is heated at 80° C. with stirring for 24 hours, giving 2.6 g of N-(4-benzoylphenyl)-2-(2-chloroethoxy)acetamide as brown oil. ESI 318.

Sources & evidence

ORD record: ord-0e06102fc63742b1a5149bd7d2a933fb
Source dataset: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07687624B2

Reaction notes

Loading…