Ethanol → HCID 23332059, compound

HRID 224690Notes

Reaction equation

HRID 224690 reaction equation
[CH2:1]([C:8]1[S:12][C:11]([C:13](=[O:17])[C:14]([O-:16])=[O:15])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[K+].O1CCOCC1.C(O)C>O>[CH2:1]([C:8]1[S:12][C:11]([C:13](=[O:17])[C:14]([OH:16])=[O:15])=[CH:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

6

Reactant 4

HCID 702EthanolHCID 14797Potassium HydroxideHCID 312751,4-DioxaneHCID 23332068HCID 23332068, compound

Product 1

HCID 23332059HCID 23332059, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of the 5-benzylthien-2-ylglyoxylate (1.37 g, 0.005 mole), potassium hydroxide (0.66 g, 0.01 mole), dioxane (3.3 ml), ethanol (33 ml) and H2O (6.6 ml) was stirred 3 hrs. at 27° C. The reaction mixture was concentrated and chilled to induce crystallization of 0.9 g of the potassium salt of 5-benzylthien-2-ylglyoxylic acid.

Workup

  1. customat 27° C
  2. concentrationThe reaction mixture was concentrated
  3. temperaturechilled
  4. customcrystallization of 0.9 g of the potassium salt of 5-benzylthien-2-ylglyoxylic acid

Sources & evidence

ORD record
ord-685e10397e24450097894f38ecf4c11c
Source dataset
uspto-grants-1980_11
Patent number
US04233452

Reaction notes

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